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??iPS??ú?

???iPS?????Thomas Deerinck, NCMIR/SPL

? ??λ60????????iPS????

ù?оС??????iPS????оС?iPS?????iPS??ú???

???о????328?iPS??????60С???????е???????????????

?????оС??iPS????iPS?????оС黹?????

2014???о????????iPS???????11￡??1??610??iPS??????90%iPS?????2014?????Yasuo KurimotoС

оС黹???5???Ч??21??о

??Що??iPS??iPS?о?iPS???iPS?5????80%?档

?iPS????о???Masayo Takahashi??Щ?????????

??á?????μ????

??е???Takahashi??ú??м?Щ??????5?????и??Takahashi??????

iPS?????2006ò彫????Oct4, Sox2, Klf4 c-Myc???У???????APSC????ü????????????????iPS??о???????飬???????????????iPS????????￡?о??